Participation Opportunities
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Find out about the latest participation opportunities. If you are an investigator and would like to promote your project on this page, please complete the form on the contact us page and we will contact you for more information.
Anxiety in children with autism spectrum disorder (ASD), ADHD, Tic Disorders, or genetic diagnosis of Fragile X, tuberous sclerosis or 22q11 deletions
Date posted: 14-July-2025
Sponsor: Holland Bloorview Kids Rehabilitation Hospital
Investigator:
Dr. Evdokia Anagnostou, MD
Pediatric Neurologist
A Randomized Placebo-Controlled Trial of Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents with NeurodevelopMental Disorders: The “CALM” Study
About:
A group of researchers at the Holland Bloorview Kids Rehabilitation Hospital are currently studying a medication called sertraline to help reduce anxiety in children and teens with neurodevelopmental disorders.
For more information, view the study flyer
This study has been funded by the Canadian Institutes of Health Research and has been approved by the Holland Bloorview Research Ethics Board (CTO-3573).
Resources:
Study flyer
You can participate if you are:
Children and teens between 8 and 17 years old
Diagnosed with autism spectrum disorder (ASD), ADHD, Tic Disorders, or genetic diagnosis of Fragile X, tuberous sclerosis or 22q11 deletions
Meet criteria for an anxiety disorder
Able to tolerate venipuncture (bloodwork)
Time commitment:
This study is comparing sertraline against placebo for reducing anxiety symptoms
The trial is 16 weeks long
There are 7 study visits
Study procedures include bloodwork, smartwatch technology and questionnaires
Intellectual Disabilities (e.g., Rett’s Syndrome)
Date posted: 12-May-2025
Sponsor: University of Alberta
Investigators:
Dr. Shannon Scott, RN, PhD
Professor, Faculty of Nursing
Ph. 780-492-1037
Shannon.scott@ualberta.ca
Dr. Lisa Hartling, PhD
Professor, Department of Pediatrics
Ph. 780-492-6124
Hartling@ualberta.ca
Arts-based digital knowledge translation tools for parents, on common pediatric conditions in emergency department visits
About:
A group of researchers at the University of Alberta are interested in hearing from parents of children with intellectual developmental disorders (IDD). They are seeking feedback on their newly developed resource. Parents will be asked to complete a 10 minute survey online.
This study has been funded by the Canadian Institutes of Health Research and has been approved by the University of Alberta Research Ethics Board (Pro00062904).
You can participate if you are:
A parent of a child under 18 years who has an intellectual developmental disorder (e.g. Autism Spectrum Disorder, Trisomy 21, Fragile X, Rett’s Syndrome)
Living in Canada
Able to read and write English
Time commitment:
You will be asked to complete a 10-15 minute survey online